Open AccessWhat Should the Serum Creatinine Be After Transplantation? An Approach to Integrate Donor and Recipient Information to Assess Posttransplant Kidney Function
Author(s) -
Rawan Mohammed Alsehli,
Scott O. Grebe,
Zija Jacaj,
Siwei Chen,
Stone Li,
Kelly Jean Thomas Craig,
Valérie A. Luyckx,
Thomas Mueller
Publication year - 2015
Publication title -
transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.45
H-Index - 204
eISSN - 1534-6080
pISSN - 0041-1337
DOI - 10.1097/tp.0000000000000622
Subject(s) - creatinine , transplantation , function (biology) , renal function , kidney transplantation , medicine , kidney , graft rejection , urology , biology , microbiology and biotechnology
Knowledge of an optimal expected serum creatinine (SCr) would be useful to detect early renal dysfunction after transplantation. Current measurements of posttransplant function rely on the recipient's SCr and calculations of estimated glomerular filtration rate (eGFR), based on recipient age, weight, and sex. Renal function after transplantation, however, also depends on the donor supply of functioning nephrons and adaptation in GFR of a single kidney.