Open AccessEffect of N-Acetylcysteine Pretreatment of Deceased Organ Donors on Renal Allograft Function
Author(s) -
Jean-Christophe Orban,
Hervé Quintard,
Élisabeth Cassuto,
P. Jambou,
Corine Samat-Long,
Carole Ichai
Publication year - 2015
Publication title -
transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.45
H-Index - 204
eISSN - 1534-6080
pISSN - 0041-1337
DOI - 10.1097/tp.0000000000000395
Subject(s) - medicine , dialysis , creatinine , urology , renal function , transplantation , kidney transplantation , kidney , acetylcysteine , randomized controlled trial , surgery , antioxidant , biochemistry , chemistry
Antioxidant donor pretreatment is one of the pharmacologic strategy proposed to prevent renal ischemia-reperfusion injuries and delayed graft function (DGF). The aim of the study was to investigate whether a donor pretreatment with N-acetylcysteine (NAC) reduces the incidence of DGF in adult human kidney transplant recipients.