Open AccessDifferences in Immunogenicity of HLA Antigens and the Impact of Cross-Reactivity on the Humoral Response
Author(s) -
Donna P. Lucas,
Mary S. Leffell,
Andrea A. Zachary
Publication year - 2015
Publication title -
transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.45
H-Index - 204
eISSN - 1534-6080
pISSN - 0041-1337
DOI - 10.1097/tp.0000000000000355
Subject(s) - immunogenicity , antigen , human leukocyte antigen , antibody , immunology , panel reactive antibody , medicine , transplantation
Information about differences in immunogenicity of various HLA antigens may help guide donor selection and identify mismatches to avoid for patients likely to need retransplantation. To date, antibody responses to a wide array of individual mismatched antigens have not been evaluated.