Open AccessAntithymocyte Globulin Facilitates Alloreactive T-cell Apoptosis by Means of Caspase-3
Author(s) -
Chethan Ashokkumar,
Qing Sun,
Mylarappa Ningappa,
Brandon W. Higgs,
George Mazariegos,
Adriana Zeevi,
Rakesh Sindhi
Publication year - 2015
Publication title -
transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.45
H-Index - 204
eISSN - 1534-6080
pISSN - 0041-1337
DOI - 10.1097/tp.0000000000000289
Subject(s) - apoptosis , caspase , globulin , immunology , microbiology and biotechnology , biology , programmed cell death , genetics
Alloreactive T-cell apoptosis may explain reduced immunosuppression requirements with proapoptotic immunosuppression and among rejection-free recipients. This possibility remains unproven.