Open AccessPreemptive Application of Airway Pressure Release Ventilation Prevents Development of Acute Respiratory Distress Syndrome in a Rat Traumatic Hemorrhagic Shock Model
Author(s) -
Somnath C. Roy,
Bryanna Emr,
Benjamin Sadowitz,
Louis A. Gatto,
Auyon Ghosh,
Joshua Satalin,
Kathy Snyder,
Lin Ge,
Guirong Wang,
William Marx,
David A. Dean,
Penny Andrews,
Anil Singh,
Thomas M. Scalea,
Nader M. Habashi,
Gary F. Nieman
Publication year - 2013
Publication title -
shock
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.095
H-Index - 117
eISSN - 1540-0514
pISSN - 1073-2322
DOI - 10.1097/shk.0b013e31829efb06
Subject(s) - ards , medicine , anesthesia , tidal volume , mechanical ventilation , respiratory distress , ventilation (architecture) , lung , respiratory system , mechanical engineering , engineering
Once established, the acute respiratory distress syndrome (ARDS) is highly resistant to treatment and retains a high mortality. We hypothesized that preemptive application of airway pressure release ventilation (APRV) in a rat model of trauma/hemorrhagic shock (T/HS) would prevent ARDS.