Open AccessInnate Immune Function Predicts the Development of Nosocomial Infection in Critically Injured Children
Author(s) -
Jennifer A. Muszynski,
Ryan A Nofziger,
Kristin Greathouse,
Jyotsteri,
Lisa Hanson-Huber,
Lisa Steele,
Kathleen Nicol,
Jonathan I. Groner,
Gail E. Besner,
Corey Raffel,
Susan Geyer,
Osama N. El-Assal,
Mark W. Hall
Publication year - 2014
Publication title -
shock
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.095
H-Index - 117
eISSN - 1540-0514
pISSN - 1073-2322
DOI - 10.1097/shk.0000000000000217
Subject(s) - medicine , innate immune system , immune system , ex vivo , intensive care unit , immunology , cytokine , sepsis , blood sampling , prospective cohort study , systemic inflammation , inflammation , in vivo , biology , microbiology and biotechnology
Critical injury has been associated with reduction in innate immune function in adults, with infection risk being related to degree of immune suppression. This relationship has not been reported in critically injured children.