Open AccessHIV-1 Infection of Female Genital Tract Tissue for Use in Prevention Studies
Author(s) -
Charlene S. Dezzutti,
Kevin Uranker,
Katherine Bunge,
Nicola Richardson-Harman,
Ingrid Macio,
Sharon L. Hillier
Publication year - 2013
Publication title -
journal of acquired immune deficiency syndromes
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.162
H-Index - 157
eISSN - 1944-7884
pISSN - 1525-4135
DOI - 10.1097/qai.0b013e318291f331
Subject(s) - ex vivo , microbicide , medicine , immunohistochemistry , in vivo , vagina , biopsy , pathology , human immunodeficiency virus (hiv) , biology , immunology , surgery , microbiology and biotechnology
Ex vivo HIV-1 challenge has been proposed as a bioindicator of microbicide product effectiveness. The objective of this study was to establish optimal parameters for use of female genital tract tissue in this model.