Open AccessHigh Viral Load and Elevated Angiogenic Markers Associated With Increased Risk of Preeclampsia Among Women Initiating Highly Active Antiretroviral Therapy in Pregnancy in the Mma Bana Study, Botswana
Author(s) -
Kathleen M. Powis,
Thomas F. McElrath,
Michael D. Hughes,
Anthony Ogwu,
Sajini Souda,
Saul A. Datwyler,
Erik von Widenfelt,
Sikhulile Moyo,
Marisa Nádas,
Joseph Makhema,
E Machakaire,
Shahin Lockman,
Max Essex,
Roger Shapiro
Publication year - 2013
Publication title -
journal of acquired immune deficiency syndromes
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.162
H-Index - 157
eISSN - 1944-7884
pISSN - 1525-4135
DOI - 10.1097/qai.0b013e318286d77e
Subject(s) - preeclampsia , medicine , zidovudine , nevirapine , viral load , lamivudine , lopinavir , odds ratio , pregnancy , abacavir , soluble fms like tyrosine kinase 1 , ritonavir , obstetrics , placental growth factor , immunology , viral disease , human immunodeficiency virus (hiv) , antiretroviral therapy , biology , genetics , hepatitis b virus , virus
Risk factors associated with preeclampsia in HIV-infected women remain largely unknown. Systemic angiogenic imbalance contributes to preeclampsia in HIV-uninfected women, but changes in angiogenic markers after highly active antiretroviral therapy (HAART) initiation have not been studied.