Open AccessHIV Replication, Inflammation, and the Effect of Starting Antiretroviral Therapy on Plasma Asymmetric Dimethylarginine, a Novel Marker of Endothelial Dysfunction
Author(s) -
Jason V. Baker,
Jacqueline Neuhaus,
Daniel Duprez,
Matthew S. Freiberg,
José I. Bernardino,
Andrew D. Badley,
Daniel E. Nixon,
Jens D. Lundgren,
Russell P. Tracy,
James D. Neaton
Publication year - 2012
Publication title -
journal of acquired immune deficiency syndromes
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.162
H-Index - 157
eISSN - 1944-7884
pISSN - 1525-4135
DOI - 10.1097/qai.0b013e318252f99f
Subject(s) - asymmetric dimethylarginine , endothelial dysfunction , interquartile range , medicine , platelet activation , confidence interval , gastroenterology , inflammation , immunology , c reactive protein , viral load , randomized controlled trial , endothelial activation , platelet , human immunodeficiency virus (hiv) , biology , arginine , biochemistry , amino acid
HIV infection is associated with premature development of cardiovascular disease. Understanding the effects of HIV replication on endothelial dysfunction and platelet activation may identify treatment targets to reduce cardiovascular disease risk.