Open AccessCCR5 Expression Is Elevated on Endocervical CD4+ T Cells in Healthy Postmenopausal Women
Author(s) -
Amie L. Meditz,
Kerrie L. Moreau,
Samantha MaWhinney,
Wendolyn S. Gozansky,
Kelsey Melander,
Wendy M. Kohrt,
Margaret E. Wierman,
Elizabeth Connick
Publication year - 2012
Publication title -
journal of acquired immune deficiency syndromes
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.162
H-Index - 157
eISSN - 1944-7884
pISSN - 1525-4135
DOI - 10.1097/qai.0b013e31823fd215
Subject(s) - medicine , cervix , gynecology , menopause , confounding , cxcr4 , postmenopausal women , gastroenterology , chemokine , obstetrics , cancer , inflammation
New HIV-1 infections are increasing in older American women largely through heterosexual transmission. Activated CD4+ T cells and CCR5 expression are linked to HIV-1 susceptibility, but whether these parameters are altered in the cervix of older women is unknown.