Open AccessComparative Effectiveness of Initial Antiretroviral Therapy Regimens
Author(s) -
Michael J. Mugavero,
Margaret May,
Heather J. Ribaudo,
Roy M. Gulick,
Sharon A. Riddler,
Richard Haubrich,
Sonia Napravnik,
Sophie Abgrall,
Andrew Phillips,
Ross Harris,
M. John Gill,
Frank de Wolf,
Robert S. Hogg,
Huldrych F. Günthard,
Geneviève Chêne,
Antonella d’Arminio Monforte,
Jodie L Guest,
Colette Smith,
Javier Murillas,
Juan Berenguer,
Christoph Wyen,
Peré Domingo,
Mari M. Kitahata,
Jonathan A C Sterne,
Michael S. Saag
Publication year - 2011
Publication title -
journal of acquired immune deficiency syndromes
Language(s) - English
Resource type - Journals
eISSN - 1944-7884
pISSN - 1525-4135
DOI - 10.1097/qai.0b013e318230372e
Subject(s) - abacavir , medicine , efavirenz , lopinavir , confidence interval , odds ratio , hazard ratio , cohort , viral load , antiretroviral therapy , human immunodeficiency virus (hiv) , immunology
The generalizability of antiretroviral therapy (ART) clinical trial efficacy findings to routine care settings is not well studied. We compared the relative effectiveness of initial ART regimens estimated in AIDS Clinical Trial Group (ACTG) randomized controlled trials with that among patients receiving ART at Antiretroviral Therapy Cohort Collaboration (ART-CC) study sites.