Open AccessAdipose Tissue and Metabolic Factors Associated With Steatosis in HIV/HCV Coinfection: Histology Versus Magnetic Resonance Spectroscopy
Author(s) -
Alireza Ghotb,
Susan M. Noworolski,
Erin Madden,
Rebecca Scherzer,
Aliya Qayyum,
Jane Pannell,
Linda D. Ferrell,
Marion G. Peters,
Phyllis C. Tien
Publication year - 2010
Publication title -
journal of acquired immune deficiency syndromes
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.162
H-Index - 157
eISSN - 1944-7884
pISSN - 1525-4135
DOI - 10.1097/qai.0b013e3181e1d963
Subject(s) - steatosis , adipose tissue , medicine , insulin resistance , fatty liver , pathology , in vivo magnetic resonance spectroscopy , histology , hepatitis c virus , liver biopsy , biopsy , endocrinology , gastroenterology , magnetic resonance imaging , insulin , immunology , radiology , virus , disease
Hepatic steatosis is common in persons with HIV and hepatitis C virus (HCV); yet biopsy measurement of steatosis is prone to sampling error. We compared magnetic resonance spectroscopy (MRS) measurement of steatosis to histology in HIV/HCV-coinfected patients and explored the associated adipose tissue and metabolic factors.