Open AccessDurability of Initial Antiretroviral Therapy in a Resource-Constrained Setting and the Potential Need for Zidovudine Weight-Based Dosing
Author(s) -
James H. Willig,
Juan Echevarría,
Andrew O. Westfall,
David Iglesias,
German Henostroza,
Carlos Seas,
Michael J. Mugavero,
Jeroan J. Allison,
Jorge Paz,
F. Martin Hernandez,
C Tomatis,
Michael S. Saag,
Eduardo Gotuzzo
Publication year - 2010
Publication title -
journal of acquired immune deficiency syndromes
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.162
H-Index - 157
eISSN - 1944-7884
pISSN - 1525-4135
DOI - 10.1097/qai.0b013e3181bc0f10
Subject(s) - didanosine , discontinuation , regimen , zidovudine , medicine , hazard ratio , stavudine , reverse transcriptase inhibitor , viral load , confidence interval , surgery , human immunodeficiency virus (hiv) , immunology , antiretroviral therapy , viral disease
Anal intraepithelial neoplasia (AIN), particularly AIN 3 is a precursor to anal cancer. Most cases of AIN are intraanal, but few treatments for intraanal AIN are currently available. Topical 85% trichloroacetic acid (TCA) is an inexpensive method used to treat perianal condyloma, a form of AIN 1, but its efficacy to treat intraanal AIN as first-line therapy is unknown.