Open AccessEffect of Baseline CD4 Cell Counts on the Clinical Significance of Short-Term Immunologic Response to Antiretroviral Therapy in Individuals With Virologic Suppression
Author(s) -
David Moore,
Ross Harris,
Viviane D. Lima,
Bob Hogg,
Margaret May,
Benita Yip,
Amy C. Justice,
Amanda Mocroft,
Peter Reiss,
Fiona Lampe,
Geneviève Chêne,
Dominique Costagliola,
Luigia Elzi,
Michael J. Mugavero,
Antonella d’Arminio Monforte,
Caroline Sabin,
Daniel Podzamczer,
Gerd Fätkenheuer,
Schlomo Staszewski,
John Gill,
Jonathan A C Sterne
Publication year - 2009
Publication title -
journal of acquired immune deficiency syndromes
Language(s) - English
Resource type - Journals
eISSN - 1944-7884
pISSN - 1525-4135
DOI - 10.1097/qai.0b013e3181b62933
Subject(s) - cart , medicine , hazard ratio , confidence interval , viral load , proportional hazards model , cohort , antiretroviral therapy , cohort study , immunology , gastroenterology , human immunodeficiency virus (hiv) , mechanical engineering , engineering
Achieving virologic suppression is a clear therapeutic goal for patients receiving combination antiretroviral therapy (cART). However, the effects of immunologic responses, whether measured as CD4 count changes from baseline or CD4 counts at follow-up, in patients with virologic suppression, have not been clearly established.