
The Acute Effects of HIV Protease Inhibitors on Insulin Suppression of Glucose Production in Healthy HIV-Negative Men
Author(s) -
Grace A. Lee,
Jean-Marc Schwarz,
Sophie Patzek,
Seung Ki Kim,
Artem Dyachenko,
Ming Wen,
Kathleen Mulligan,
Morris Schambelan,
Carl Grünfeld
Publication year - 2009
Publication title -
journal of acquired immune deficiency syndromes
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.162
H-Index - 157
eISSN - 1944-7884
pISSN - 1525-4135
DOI - 10.1097/qai.0b013e3181b03214
Subject(s) - amprenavir , indinavir , insulin resistance , medicine , ritonavir , insulin , endocrinology , placebo , protease inhibitor (pharmacology) , glucose clamp technique , pharmacology , protease , biology , pancreatic hormone , human immunodeficiency virus (hiv) , immunology , hiv 1 protease , viral load , enzyme , biochemistry , antiretroviral therapy , alternative medicine , pathology
The effects of different HIV protease inhibitors (PIs) on peripheral insulin resistance have been described, but less is known about their effects on insulin suppression of endogenous glucose production (EGP).