Open AccessFish Oil and Fenofibrate for the Treatment of Hypertriglyceridemia in HIV-Infected Subjects on Antiretroviral Therapy
Author(s) -
John G. Gerber,
Douglas Kitch,
Carl J. Fichtenbaum,
Robert Zackin,
Stéphannie Charles,
Evelyn Hogg,
Edward P. Acosta,
Elizabeth Connick,
David A. Wohl,
Erna M. Kojic,
Constance A. Benson,
Judith A. Aberg
Publication year - 2008
Publication title -
journal of acquired immune deficiency syndromes
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.162
H-Index - 157
eISSN - 1944-7884
pISSN - 1525-4135
DOI - 10.1097/qai.0b013e31815bace2
Subject(s) - fenofibrate , fish oil , hypertriglyceridemia , medicine , triglyceride , gastroenterology , combination therapy , lipoprotein , cholesterol , fish <actinopterygii> , biology , fishery
Fish oil has been shown to reduce serum triglyceride (TG) concentrations. In HIV-infected patients on antiretroviral therapy, high TG concentrations likely contribute to increased risk of cardiovascular disease. AIDS Clinical Trials Group A5186 examined the safety and efficacy of fish oil plus fenofibrate in subjects not achieving serum TG levels < or =200 mg/dL with either agent alone.