Open AccessHigh MIP-1β Levels in Plasma Predict Long-Term Immunological Nonresponse to Suppressive Antiretroviral Therapy in HIV Infection
Author(s) -
Christian Prebensen,
Thor Ueland,
Annika E. Michelsen,
Andreas Lind,
Frank Olav Pettersen,
Tom Eirik Mollnes,
Pål Aukrust,
Anne Ma DyrholRiise,
Dag Kvale
Publication year - 2015
Publication title -
journal of acquired immune deficiency syndromes
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.162
H-Index - 157
eISSN - 1944-7884
pISSN - 1525-4135
DOI - 10.1097/qai.0000000000000617
Subject(s) - interquartile range , medicine , confidence interval , odds ratio , immunology , cohort , gastroenterology , viral load , antiretroviral therapy , human immunodeficiency virus (hiv)
HIV-infected patients who fail to reconstitute their CD4 T-cell counts during suppressive antiretroviral therapy (ART) have increased risk of both AIDS-related and non-AIDS-related morbidity and mortality. Improved understanding of immunological nonresponse (INR) is necessary to enable earlier clinical intervention.