Open AccessAbdominal Obesity Contributes to Neurocognitive Impairment in HIV-Infected Patients With Increased Inflammation and Immune Activation
Author(s) -
Fred R. Sattler,
Jun He,
Scott Letendre,
Cara C. Wilson,
Chelsea Sanders,
Robert K. Heaton,
Ronald J. Ellis,
Dean Franklin,
Grace M. Aldrovandi,
Christina M. Marra,
David B. Clifford,
Susan Morgello,
Igor Grant,
J. Allen McCutchan
Publication year - 2015
Publication title -
journal of acquired immune deficiency syndromes
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.162
H-Index - 157
eISSN - 1944-7884
pISSN - 1525-4135
DOI - 10.1097/qai.0000000000000458
Subject(s) - neurocognitive , medicine , abdominal obesity , waist , inflammation , systemic inflammation , biomarker , immune system , body mass index , obesity , gastroenterology , immunology , cognition , biochemistry , psychiatry , chemistry
We tested our hypothesis that abdominal obesity when associated with increased levels of systemic and central nervous system immunoinflammatory mediators contributes to neurocognitive impairment (NCI).