Open AccessLongitudinal Trends in HIV Nonoccupational Postexposure Prophylaxis Use at a Boston Community Health Center Between 1997 and 2013
Author(s) -
Sachin Jain,
Catherine E. Oldenburg,
Matthew J. Mimiaga,
Kenneth H. Mayer
Publication year - 2015
Publication title -
journal of acquired immune deficiency syndromes
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.162
H-Index - 157
eISSN - 1944-7884
pISSN - 1525-4135
DOI - 10.1097/qai.0000000000000403
Subject(s) - odds , medicine , odds ratio , regimen , men who have sex with men , human immunodeficiency virus (hiv) , community health center , post exposure prophylaxis , retrospective cohort study , family medicine , demography , gerontology , surgery , logistic regression , syphilis , sociology
Secular trends in nonoccupational postexposure prophylaxis (NPEP) use have not been well characterized. We performed a retrospective longitudinal study of 894 electronic medical records of NPEP users, mostly men who have sex with men, at a Boston community health center who presented between July 1997 and August 2013. NPEP use and condomless sexual exposures increased over time; 19.4% had multiple NPEP courses. Having an HIV-infected partner was associated with increased odds of regimen completion, and 3-drug regimens were associated with decreased odds of completion. Targeted adherence and risk-reduction counseling are warranted for select NPEP users at this center.