Open AccessDiagnostic Accuracy of a Rapid Urine Lipoarabinomannan Test for Tuberculosis in HIV-Infected Adults
Author(s) -
Lydia Nakiyingi,
Vineshree Mischka Moodley,
Yukari C. Manabe,
Mark P. Nicol,
Molly Holshouser,
Derek T Armstrong,
Widaad Zemanay,
Welile Sikhondze,
Olive Mbabazi,
Bareng A. S. yane,
Maunank Shah,
Moses Joloba,
David Alland,
Jerrold J. Ellner,
Susan E. Dorman
Publication year - 2014
Publication title -
journal of acquired immune deficiency syndromes
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.162
H-Index - 157
eISSN - 1944-7884
pISSN - 1525-4135
DOI - 10.1097/qai.0000000000000151
Subject(s) - lipoarabinomannan , medicine , tuberculosis , sputum , mycobacterium tuberculosis , urine , tuberculosis diagnosis , odds ratio , sputum culture , prospective cohort study , immunology , pathology
In settings of high HIV prevalence, tuberculosis control and patient management are hindered by lack of accurate, rapid tuberculosis diagnostic tests that can be performed at point-of-care. The Determine TB LAM Ag (TB LAM) test is a lateral flow immunochromatographic test for detection of mycobacterial lipoarabinomannan (LAM) in urine. Our objective was to determine sensitivity and specificity of the TB LAM test for tuberculosis diagnosis.