Open AccessImmune Activation Is Associated With Increased Gut Microbial Translocation in Treatment-Naive, HIV-Infected Children in a Resource-Limited Setting
Author(s) -
Sudheesh Pilakka-Kanthikeel,
Kris Arheart,
Anbalagan Selvaraj,
Soumya Swaminathan,
Savita Pahwa
Publication year - 2014
Publication title -
journal of acquired immune deficiency syndromes
Language(s) - English
Resource type - Journals
eISSN - 1944-7884
pISSN - 1525-4135
DOI - 10.1097/qai.0000000000000096
Subject(s) - cd14 , immune system , viral load , immunology , cd8 , viremia , biology , t cell , antiretroviral therapy , cd4 cd8 ratio , medicine , human immunodeficiency virus (hiv) , lymphocyte subsets
Gut damage resulting in microbial translocation (MT) is considered a major cause of immune activation (IA) in HIV infection, but data in children are limited, particularly in the absence of antiretroviral therapy.