Open AccessRealtime adherence monitoring of antiretroviral therapy among hiv-infected adults and children in rural uganda
Author(s) -
Jessica Haberer,
Julius Kiwanuka,
Denis Nansera,
Conrad Muzoora,
Peter W. Hunt,
Jacquelyn So,
Michael J. O’Donnell,
Mark J. Siedner,
Jeffrey N. Martin,
David R. Bangsberg
Publication year - 2013
Publication title -
aids
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.195
H-Index - 216
eISSN - 1473-5571
pISSN - 0269-9370
DOI - 10.1097/qad.0b013e328363b53f
Subject(s) - medicine , short message service , antiretroviral therapy , human immunodeficiency virus (hiv) , odds , odds ratio , pediatrics , viral load , family medicine , telecommunications , logistic regression , computer science
A real-time wireless electronic adherence monitor (EAM) and weekly self-report of missed doses via interactive voice response (IVR) and short message service (SMS) queries were used to measure antiretroviral therapy adherence in 49 adults and 46 children in rural Uganda. Median adherence was 89.5% among adults and 92.8% among children by EAM, and 99-100% for both adults and children by IVR/SMS self-report. Loss of viral suppression was significantly associated with adherence by EAM (odds ratio 0.58 for each 10% increase), but not IVR/SMS. Wireless EAM creates an exciting opportunity to monitor and potentially intervene with adherence challenges as they are happening.