Open AccessHIV-1 outcompetes HIV-2 in dually infected Senegalese individuals with low CD4+ cell counts
Author(s) -
Da. Raugi,
Geoffrey S. Gottlieb,
Papa Salif Sow,
Macoumba Touré,
Fatima Sall,
Awa Gaye,
Ibra Ndoye,
Nancy B. Kiviat,
Stephen E. Hawes
Publication year - 2013
Publication title -
aids
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.195
H-Index - 216
eISSN - 1473-5571
pISSN - 0269-9370
DOI - 10.1097/qad.0b013e328362e856
Subject(s) - viral load , immunology , lentivirus , peripheral blood mononuclear cell , medicine , immunopathology , viral disease , sida , semen , cohort study , cohort , biology , human immunodeficiency virus (hiv) , virology , andrology , biochemistry , in vitro
Dual infection with HIV-1 and HIV-2, which is not uncommon in West Africa, has implications for transmission, progression, and antiretroviral therapy (ART). Few studies have examined viral dynamics in this setting. Our objective was to directly compare HIV-1 and HIV-2 viral loads and to examine whether this relationship is associated with CD4⁺ cell count.