
Dendritic cell-specific intercellular adhesion molecule-3 grabbing nonintegrin mediates HIV-1 infection of and transmission by M2a-polarized macrophages in vitro
Author(s) -
Edana Cassol,
Luca Cassetta,
Chiara Rizzi,
Dana Gabuzda,
Massimo Alfano,
Guido Poli
Publication year - 2013
Publication title -
aids
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.195
H-Index - 216
eISSN - 1473-5571
pISSN - 0269-9370
DOI - 10.1097/qad.0b013e32835cfc82
Subject(s) - chemistry , chemokine , flow cytometry , dc sign , chemokine receptor , dendritic cell , microbiology and biotechnology , in vitro , monocyte , receptor , antigen , immunology , biology , biochemistry
To assess in-vitro effects of monocyte-derived macrophage (MDM) polarization into M1 and M2a cells on HIV-1 replication and transmission and obtain new insights into the potential importance of macrophage polarization in vivo.