Open AccessLong-acting nanoformulated antiretroviral therapy elicits potent antiretroviral and neuroprotective responses in HIV-1-infected humanized mice
Author(s) -
Prasanta K. Dash,
Howard E. Gendelman,
Upal Roy,
Shantanu Balkundi,
Yazen Alnouti,
R. Lee Mosley,
Harris A. Gelbard,
JoEllyn M McMillan,
Santhi Gorantla,
Larisa Y. Poluektova
Publication year - 2012
Publication title -
aids
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.195
H-Index - 216
eISSN - 1473-5571
pISSN - 0269-9370
DOI - 10.1097/qad.0b013e328357f5ad
Subject(s) - pharmacology , medicine , viral load , ritonavir , humanized mouse , immunology , immune system , virus , antiretroviral therapy
Long-acting nanoformulated antiretroviral therapy (nanoART) with improved pharmacokinetics, biodistribution and limited systemic toxicities will likely improve drug adherence and access to viral reservoirs.