Open AccessCerebrospinal fluid HIV escape associated with progressive neurologic dysfunction in patients on antiretroviral therapy with well controlled plasma viral load
Author(s) -
Michael J. Peluso,
Francesca Ferretti,
Julia Peterson,
Evelyn Lee,
Dietmar Fuchs,
Antonio Boschini,
Magnus Gisslén,
Nancy R. Angoff,
Richard W. Price,
Paola Cinque,
Serena Spudich
Publication year - 2012
Publication title -
aids
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.195
H-Index - 216
eISSN - 1473-5571
pISSN - 0269-9370
DOI - 10.1097/qad.0b013e328355e6b2
Subject(s) - cerebrospinal fluid , antiretroviral therapy , medicine , viral load , lentivirus , human immunodeficiency virus (hiv) , viral disease , sida , virology , immunology , pathology
To characterize HIV-infected patients with neurosymptomatic cerebrospinal fluid (CSF) 'escape', defined as detectable CSF HIV RNA in the setting of treatment-suppressed plasma levels or CSF RNA more than 1-log higher than plasma RNA.