Open AccessPrevalent tuberculosis and mortality among HAART initiators
Author(s) -
Daniel Westreich,
Matthew P. Fox,
Annelies Van Rie,
Mhairi Maskew
Publication year - 2012
Publication title -
aids
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.195
H-Index - 216
eISSN - 1473-5571
pISSN - 0269-9370
DOI - 10.1097/qad.0b013e328351f6b8
Subject(s) - tuberculosis , medicine , proportional hazards model , hazard ratio , cohort , antiretroviral therapy , multivariate analysis , human immunodeficiency virus (hiv) , cohort study , mortality rate , immunology , viral load , confidence interval , pathology
The effect of tuberculosis on mortality in people initiating highly-active antiretroviral therapy (HAART) remains unclear; here, we strengthened a previous cohort analysis. Multivariate Cox proportional hazards models were used to assess the association of baseline tuberculosis and time to all-cause mortality among HAART initiators. In reanalysis, treatment for tuberculosis at time of HAART initiation remained unassociated with increased risks of all-cause mortality, with adjusted hazard ratios ranging from 1.00 to 1.09.