Open AccessEffects of lifestyle modification and metformin on atherosclerotic indices among HIV-infected patients with the metabolic syndrome
Author(s) -
Kathleen V. Fitch,
Suhny Abbara,
Hang Lee,
Eleni Stavrou,
Rachel Sacks,
Theresa Hoskins Michel,
Linda Hemphill,
Martin Torriani,
Steven Grinspoon
Publication year - 2012
Publication title -
aids
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.195
H-Index - 216
eISSN - 1473-5571
pISSN - 0269-9370
DOI - 10.1097/qad.0b013e32834f33cc
Subject(s) - metformin , medicine , metabolic syndrome , placebo , insulin resistance , dyslipidemia , diabetes mellitus , gastroenterology , population , c reactive protein , endocrinology , obesity , inflammation , insulin , pathology , alternative medicine , environmental health
Metabolic abnormalities including diabetes, dyslipidemia, hypertension, and abdominal obesity occur commonly in HIV patients, are associated with increased coronary artery calcification (CAC), and contribute to increased cardiovascular disease (CVD) in this population. We hypothesized that lifestyle modification (LSM) and metformin would improve CVD indices in HIV patients with metabolic syndrome.