Open AccessMarkers of endothelial dysfunction, coagulation and tissue fibrosis independently predict venous thromboembolism in HIV
Author(s) -
Laura W. Musselwhite,
Virginia Sheikh,
Thomas Norton,
Adam Rupert,
Brian Porter,
Scott Penzak,
Jeff Skinner,
JoAnn M. Mican,
Colleen Hadigan,
Irini Sereti
Publication year - 2011
Publication title -
aids
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.195
H-Index - 216
eISSN - 1473-5571
pISSN - 0269-9370
DOI - 10.1097/qad.0b013e3283453fcb
Subject(s) - medicine , immunology , fibrosis , gastroenterology , thrombosis , coagulopathy , venous thrombosis
HIV infection is associated with coagulation abnormalities and significantly increased risk of venous thrombosis. It has been shown that higher plasma levels of coagulation and inflammatory biomarkers predicted mortality in HIV. We investigated the relationship between venous thrombosis and HIV-related characteristics, traditional risk factors of hypercoagulability, and pre-event levels of biomarkers.