Open AccessThe contribution of HIV-discordant relationships to new HIV infections in Rakai, Uganda
Author(s) -
Ron Gray,
Victor Ssempiija,
James D Shelton,
David Serwadda,
Fred Nalugoda,
Joseph Kagaayi,
Godfrey Kigozi,
Maria J. Wawer
Publication year - 2011
Publication title -
aids
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.195
H-Index - 216
eISSN - 1473-5571
pISSN - 0269-9370
DOI - 10.1097/qad.0b013e3283448790
Subject(s) - human immunodeficiency virus (hiv) , medicine , cohort , antiretroviral therapy , lentivirus , sida , voluntary counseling and testing , cohort study , virology , immunology , demography , viral disease , population , viral load , environmental health , health services , health facility , sociology
We determined HIV infections in the Rakai cohort before (82/9434) and after (131/13082) the availability of antiretroviral therapy (ART). The proportions of total HIV infections pre-ART and post-ART were 18.3% and 13.7%, respectively, among identifiable HIV-discordant couples, 23.2% and 26.0%, respectively, in concordant HIV-negative couples, 29.3% and 17.6% in married persons with unknown partner status, and 29.3% and 42.7% in the unmarried. Voluntary counseling and testing targeting discordant couples is unlikely to have a substantial impact in this setting.