Open AccessHypertriglyceridemia in combination antiretroviral-treated HIV-positive individuals: potential impact on HIV sensory polyneuropathy
Author(s) -
Sugato Banerjee,
J. Allen McCutchan,
Beau M. Ances,
Reena Deutsch,
Patricia K. Riggs,
Lauren Way,
Ronald J. Ellis
Publication year - 2011
Publication title -
aids
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.195
H-Index - 216
eISSN - 1473-5571
pISSN - 0269-9370
DOI - 10.1097/qad.0b013e328341dd68
Subject(s) - medicine , hypertriglyceridemia , odds ratio , peripheral neuropathy , diabetes mellitus , sensory neuropathy , prospective cohort study , gastroenterology , cohort study , endocrinology , triglyceride , cholesterol
in HIV populations that are aging due to improved longevity with combination antiretroviral therapy (CART), both hypertriglyceridemia (hTRG) and sensory neuropathy have become increasingly common. Sensory neuropathy is associated with substantial long-term disability and frequently requires management with analgesics. Elevated serum triglycerides (TRGs) are associated with an increased risk for sensory neuropathy in diabetes mellitus. However, the contribution of hTRG to sensory neuropathy in HIV has not been carefully evaluated.