Open AccessA single tablet regimen is associated with higher adherence and viral suppression than multiple tablet regimens in HIV+ homeless and marginally housed people
Author(s) -
David R. Bangsberg,
Kathleen Ragland,
Alex Monk,
Steven G. Deeks
Publication year - 2010
Publication title -
aids
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.195
H-Index - 216
eISSN - 1473-5571
pISSN - 0269-9370
DOI - 10.1097/qad.0b013e328340a209
Subject(s) - efavirenz , medicine , regimen , pill , viral load , population , cohort , confounding , randomized controlled trial , hiv drug resistance , human immunodeficiency virus (hiv) , oncology , immunology , pharmacology , antiretroviral therapy , environmental health
Although, single-tablet regimen (STR) efavirenz, emtricibine, and tenofovir disoproxil fumarate (EFV/FTC/TDF) may be appealing in HIV-infected persons who are at high risk for nonadherence, the degree to which this simplified formulation affects adherence is not known. The virologic effectiveness of this STR in a potentially nonadherent population remains a concern, given the rapid selection of drug resistance seen with these drugs.