Open AccessImmune activation, apoptosis, and Treg activity are associated with persistently reduced CD4+ T-cell counts during antiretroviral therapy
Author(s) -
Stefania Piconi,
Daria Trabattoni,
Andrea Gori,
Serena Parisotto,
C. Magni,
Paola Meraviglia,
Alessandra Bandera,
Amedeo Capetti,
Giuliano Rizzardini,
Mario Clerici
Publication year - 2010
Publication title -
aids
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.195
H-Index - 216
eISSN - 1473-5571
pISSN - 0269-9370
DOI - 10.1097/qad.0b013e32833c93ce
Subject(s) - immunology , immune system , viremia , foxp3 , peripheral blood mononuclear cell , cd8 , tlr2 , t cell , biology , apoptosis , medicine , tlr4 , antibody , in vitro , biochemistry
Persistently reduced CD4(+) T-lymphocyte counts in the face of undetectable HIV viremia are seen in a sizable percentage of HIV-infected patients undergoing antiretroviral therapy (ART). We analyzed the immune correlates of this phenomenon.