Open AccessThe impact of active HIV-1 replication on the physiological age-related decline of immature-transitional B-cells in HIV-1 infected children
Author(s) -
Alberto Cagigi,
Paolo Palma,
Anilsson,
Silvia Di Cesare,
Simone Pensieroso,
Maria Kakoulidou,
Stefania Bernardi,
Paolo Rossi,
Francesca Chiodi
Publication year - 2010
Publication title -
aids
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.195
H-Index - 216
eISSN - 1473-5571
pISSN - 0269-9370
DOI - 10.1097/qad.0b013e32833c3298
Subject(s) - c c chemokine receptor type 7 , viremia , cxcr4 , immunology , cxcr5 , biology , flow cytometry , viral replication , virology , chemokine , human immunodeficiency virus (hiv) , chemokine receptor , virus , immune system
To characterize the level of immature-transitional B-cells in blood during pediatric HIV-1 infection in relation to active or suppressed viremia. We also aimed at characterizing the level of expression of CXCR4, CXCR5 and CCR7 on immature-transitional B-cells, as these receptors are important mediators for homing of B-cells.