Combinatorial content of CCL3L and CCL4L gene copy numbers influence HIV-AIDS susceptibility in Ukrainian children | Zendy

Ludmila Shostakovich-Koretskaya | Zendy; Gabriel Catano | Zendy; Z. A. Chykarenko | Zendy; Weijing He | Zendy; Germán G. Gornalusse | Zendy; Srinivas Mummidi | Zendy; Racquel Sanchez | Zendy; Matthew J. Dolan | Zendy; Seema S. Ahuja | Zendy; Robert A. Clark | Zendy; Hemant Kulkarni | Zendy; Sunil K. Ahuja | Zendy

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Combinatorial content of CCL3L and CCL4L gene copy numbers influence HIV-AIDS susceptibility in Ukrainian children

Author(s) -

Ludmila Shostakovich-Koretskaya,

Gabriel Catano,

Z. A. Chykarenko,

Weijing He,

Germán G. Gornalusse,

Srinivas Mummidi,

Racquel Sanchez,

Matthew J. Dolan,

Seema S. Ahuja,

Robert A. Clark,

Hemant Kulkarni,

Sunil K. Ahuja

Publication year - 2009

Publication title -

aids

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.195

H-Index - 216

eISSN - 1473-5571

pISSN - 0269-9370

DOI - 10.1097/qad.0b013e3283270b3f

Subject(s) - ukrainian , virology , lentivirus , human immunodeficiency virus (hiv) , genetics , biology , viral disease , philosophy , linguistics

CCL3L and CCL4L genes encode HIV-suppressive chemokines, colocalize on chromosome 17q12 and have copy number variation. Copy number variation of CCL3L associates with HIV-AIDS susceptibility. Here, we determined the influence of the combinatorial content of distinct CCL3L and CCL4L genes on HIV-AIDS susceptibility.

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