Open AccessTransmission networks of drug resistance acquired in primary/early stage HIV infection
Author(s) -
Bluma G. Brenner,
Michel Roger,
Daniela Moïsi,
Maureen Oliveira,
Isabelle Hardy,
Reuven Turgel,
Hugues Charest,
JeanPierre Routy,
Mark A. Wainberg
Publication year - 2008
Publication title -
aids
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.195
H-Index - 216
eISSN - 1473-5571
pISSN - 0269-9370
DOI - 10.1097/qad.0b013e3283121c90
Subject(s) - transmission (telecommunications) , reverse transcriptase , drug resistance , biology , virology , population , cluster (spacecraft) , genetics , polymerase chain reaction , medicine , gene , environmental health , computer science , electrical engineering , programming language , engineering
Population-based sequencing of primary/recent HIV infections (PHIs) can provide a framework for understanding transmission dynamics of local epidemics. In Quebec, half of PHIs represent clustered transmission events. This study ascertained the cumulative implications of clustering on onward transmission of drug resistance.