Open AccessRole of HIV and human herpesvirus-8 infection in pulmonary arterial hypertension
Author(s) -
Priscilla Y. Hsue,
Steven G. Deeks,
Husam H. Farah,
Swapna Palav,
Samira Y Ahmed,
Audrey H. Schnell,
Allison Ellman,
Laurence Huang,
Sheila C. Dollard,
Jeffrey N. Martin
Publication year - 2008
Publication title -
aids
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.195
H-Index - 216
eISSN - 1473-5571
pISSN - 0269-9370
DOI - 10.1097/qad.0b013e3282f7cd42
Subject(s) - human herpesvirus , human immunodeficiency virus (hiv) , medicine , virology , pulmonary hypertension , human herpesvirus 6 , immunology , cardiology , viral disease , herpesviridae
Previous work has found a high prevalence of pulmonary arterial hypertension in HIV-infected persons, but establishment of a causal relationship has been limited by the lack of well characterized contemporaneous HIV-uninfected comparator groups. Among HIV-uninfected persons, human herpesvirus-8 (HHV-8) has also been linked to pulmonary arterial hypertension (PAH), but whether this relationship occurs among HIV-infected persons - who have among the highest prevalence of HHV-8 infection - has not been examined.