Open AccessInsulin resistance predicts endothelial dysfunction and cardiovascular risk in HIV-infected persons on long-term highly active antiretroviral therapy
Author(s) -
Kristin Mondy,
Lisa de las Fuentes,
Alan D. Waggoner,
Nur F. Önen,
Coco Bopp,
Sherry Lassa-Claxton,
William G. Powderly,
Víctor G. DávilaRomán,
Kevin E. Yarasheski
Publication year - 2008
Publication title -
aids
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.195
H-Index - 216
eISSN - 1473-5571
pISSN - 0269-9370
DOI - 10.1097/qad.0b013e3282f70694
Subject(s) - medicine , insulin resistance , brachial artery , cohort , endothelial dysfunction , prospective cohort study , body mass index , intima media thickness , insulin , vasodilation , cardiology , diabetes mellitus , immunology , endocrinology , blood pressure , carotid arteries
Cardiovascular disease risk among persons with HIV is likely multifactorial, thus testing a variety of available noninvasive vascular ultrasound and other surrogate tests may yield differing results. To address this issue, we assessed multiple metabolic and clinical predictors of endothelial function and carotid intima-media thickness in HIV-infected subjects and compared results with HIV-negative controls.