Open AccessEffects of ritonavir and amprenavir on insulin sensitivity in healthy volunteers
Author(s) -
Grace A. Lee,
Madhu N. Rao,
Kathleen Mulligan,
Joan C. Lo,
Francesca Aweeka,
Jean-Marc Schwarz,
Morris Schambelan,
Carl Grünfeld
Publication year - 2007
Publication title -
aids
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.195
H-Index - 216
eISSN - 1473-5571
pISSN - 0269-9370
DOI - 10.1097/qad.0b013e32826fbc54
Subject(s) - amprenavir , ritonavir , medicine , virology , pharmacology , human immunodeficiency virus (hiv) , chemistry , viral load , antiretroviral therapy , protease , enzyme , biochemistry , hiv 1 protease
Some HIV protease inhibitors (PIs) have been shown to induce insulin resistance in vitro but the degree to which specific PIs affect insulin sensitivity in humans is less well understood.