Open AccessFinger-prick blood samples can be used interchangeably with venous samples for CD4 cell counting indicating their potential for use in CD4 rapid tests
Author(s) -
Calman A. MacLennan,
Joep J. G. van Oosterhout,
Sarah White,
Mark T. Drayson,
Eduard E. Zijlstra,
Malcolm E. Molyneux
Publication year - 2007
Publication title -
aids
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.195
H-Index - 216
eISSN - 1473-5571
pISSN - 0269-9370
DOI - 10.1097/qad.0b013e32823bcb03
Subject(s) - venous blood , cell counting , medicine , blood cell , immunology , human immunodeficiency virus (hiv) , pathology , cancer , cell cycle
The objective of this study was to investigate the utility of finger-prick blood samples for CD4 cell counting. We estimated agreement between CD4 cell counts in paired finger-prick and venous samples from 110 HIV-infected adults from Malawi. Bias was 6.6 cells/microl (limits of agreement -50.7 and 63.7 cells/microl) for absolute counts and 0.71% (limits of agreement -2.07 and 3.48%) for %CD4/lymphocyte suggesting that finger-prick blood samples can be used interchangeably with venous samples for CD4 cell counting.