Open AccessFinger-prick blood samples can be used interchangeably with venous samples for CD4 cell counting indicating their potential for use in CD4 rapid tests
Author(s) -
Calman A. MacLennan,
Joep JG van Oosterhout,
Sarah White,
Mark T. Drayson,
Eduard E. Zijlstra,
Malcolm E. Molyneux
Publication year - 2007
Publication title -
aids
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.195
H-Index - 216
eISSN - 1473-5571
pISSN - 0269-9370
DOI - 10.1097/qad.0b013e32823bcb03
Subject(s) - venous blood , cell counting , medicine , blood cell , immunology , human immunodeficiency virus (hiv) , pathology , cancer , cell cycle
The objective of this study was to investigate the utility of finger-prick blood samples for CD4 cell counting. We estimated agreement between CD4 cell counts in paired finger-prick and venous samples from 110 HIV-infected adults from Malawi. Bias was 6.6 cells/microl (limits of agreement -50.7 and 63.7 cells/microl) for absolute counts and 0.71% (limits of agreement -2.07 and 3.48%) for %CD4/lymphocyte suggesting that finger-prick blood samples can be used interchangeably with venous samples for CD4 cell counting.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom