Open AccessValidation of a Dye Stain Assay for Vaginally Inserted Hydroxyethylcellulose-Filled Microbicide Applicators
Author(s) -
Lauren L. Katzen,
José A. Fernández-Romero,
Avina Sarna,
Kailapuri G. Murugavel,
Daniel G. Gawarecki,
Thomas M. Zydowsky,
Barbara Mensch
Publication year - 2011
Publication title -
sexually transmitted diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.507
H-Index - 105
eISSN - 1537-4521
pISSN - 0148-5717
DOI - 10.1097/olq.0b013e31822e6160
Subject(s) - microbicide , medicine , stain , chromatography , microbiology and biotechnology , virology , pathology , staining , human immunodeficiency virus (hiv) , chemistry , biology
The reliability and validity of self-reports of vaginal microbicide use are questionable given the explicit understanding that participants are expected to comply with study protocols. Our objective was to optimize the use of Population Council's previously validated dye stain assay (DSA) and related procedures, and to establish predictive values for the DSAs ability to identify vaginally inserted single-use, low-density polyethylene microbicide applicators filled with hydroxyethylcellulose gel.