Open AccessHydrogen Peroxide–Producing Lactobacilli Are Associated With Lower Levels of Vaginal Interleukin-1β, Independent of Bacterial Vaginosis
Author(s) -
Caroline Mitchell,
David N. Fredricks,
Kathy Agnew,
Jane Hitti
Publication year - 2015
Publication title -
sexually transmitted diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.507
H-Index - 105
eISSN - 1537-4521
pISSN - 0148-5717
DOI - 10.1097/olq.0000000000000298
Subject(s) - bacterial vaginosis , lactobacillus crispatus , lactobacillus , medicine , vagina , microbiology and biotechnology , hydrogen peroxide , immunology , bacteria , biology , gynecology , biochemistry , surgery , genetics
The presence of hydrogen peroxide (H2O2)-producing lactobacilli in the vagina is associated with decreased rates of preterm birth and HIV acquisition. We hypothesize that this is due to immunomodulatory effects of these species.