Open AccessNeurosyphilis and Ophthalmic Syphilis in Persons With Negative Rapid Plasma Reagin and Positive Treponemal Antibody Test Results
Author(s) -
Susan Tuddenham,
Christiana Obeng,
Khalil G. Ghanem
Publication year - 2015
Publication title -
sexually transmitted diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.507
H-Index - 105
eISSN - 1537-4521
pISSN - 0148-5717
DOI - 10.1097/olq.0000000000000282
Subject(s) - rapid plasma reagin , medicine , syphilis , neurosyphilis , serodiscordant , congenital syphilis , syphilis serodiagnosis , obstetrics , immunology , treponema , human immunodeficiency virus (hiv) , antiretroviral therapy , viral load
The detection of serodiscordant syphilis test results raises several important clinical and public health questions. Based on our retrospective review, the probability of neurosyphilis in persons with serodiscordant serologies is low. The probability of ophthalmic syphilis may be higher, but we lack objective measures for that diagnosis.