Open AccessFailure of Azithromycin 2.0 g in the Treatment of Gonococcal Urethritis Caused by High-Level Resistance in California
Author(s) -
Severin Gose,
Olusegun O. Soge,
James L. Beebe,
Duylinh Nguyen,
Juliet Stoltey,
Heidi M. Bauer
Publication year - 2015
Publication title -
sexually transmitted diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.507
H-Index - 105
eISSN - 1537-4521
pISSN - 0148-5717
DOI - 10.1097/olq.0000000000000265
Subject(s) - medicine , urethritis , azithromycin , gonorrhea , non gonococcal urethritis , neisseria gonorrhoeae , gynecology , gonococcal infection , antibiotic resistance , sexually transmitted disease , virology , antibiotics , microbiology and biotechnology , human immunodeficiency virus (hiv) , syphilis , biology
We report a treatment failure to azithromycin 2.0 g caused by a urethral Neisseria gonorrhoeae isolate with high-level azithromycin resistance in California. This report describes the epidemiological case investigation and phenotypic and genetic characterization of the treatment failure isolate.