Open AccessUse of the Dye Stain Assay and Ultraviolet Light Test for Assessing Vaginal Insertion of Placebo-Filled Applicators Before and After Sex
Author(s) -
Marla J. Keller,
Niall Buckley,
Lauren L. Katzen,
Jennifer Walsh,
Barbara Friedland,
Sarah Littlefield,
Lin Juan,
Xiaonan Xue,
Terri L. Cornelison,
Betsy C. Herold,
Mark H. Einstein
Publication year - 2013
Publication title -
sexually transmitted diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.507
H-Index - 105
eISSN - 1537-4521
pISSN - 0148-5717
DOI - 10.1097/olq.0000000000000040
Subject(s) - medicine , dosing , placebo , stain , staining , semen , nuclear medicine , surgery , pathology , andrology , alternative medicine
Applicator dye staining and ultraviolet (UV) light have been used in trials to measure adherence, but not in the setting of before and after sex gel dosing (BAT-24). This study was designed to determine if semen or presex gel dosing impacts the sensitivity and specificity of a dye stain assay (DSA) for measuring vaginal insertion of placebo-filled applicators with BAT-24 dosing.