Open AccessGastric Rupture and Necrosis in Prader‐Willi Syndrome
Author(s) -
Stevenson David A,
Heinemann Janalee,
Angulo Moris,
Butler Merlin G,
Loker Jim,
Rupe Norma,
Kendell Patrick,
Cassidy Suzanne B,
Scheimann Ann
Publication year - 2007
Publication title -
journal of pediatric gastroenterology and nutrition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.206
H-Index - 131
eISSN - 1536-4801
pISSN - 0277-2116
DOI - 10.1097/mpg.0b013e31805b82b5
Subject(s) - medicine , vomiting , abdominal pain , necrosis , cohort , pediatrics
Hyperphagia and obesity are common features in individuals with Prader‐Willi syndrome (PWS). Demographic and cause‐of‐death data from individuals with PWS were obtained through a national support organization. Four reports of unexpected mortality due to gastric rupture and necrosis were found in 152 reported deaths, accounting for 3% of the causes of mortality. Four additional individuals were suspected to have gastric rupture. Vomiting and abdominal pain, although rare in PWS, were frequent findings in this cohort. The physician should consider an emergent evaluation for gastric rupture and necrosis in individuals with PWS who present with vomiting and abdominal pain.