Open AccessPropofol Use in Pediatric Patients With Food Allergy and Eosinophilic Esophagitis
Author(s) -
Mehta Pooja,
Sundaram Shikha S.,
Furuta Glenn T.,
Pan Zhaoxing,
Atkins Dan,
Markowitz Scott
Publication year - 2017
Publication title -
journal of pediatric gastroenterology and nutrition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.206
H-Index - 131
eISSN - 1536-4801
pISSN - 0277-2116
DOI - 10.1097/mpg.0000000000001291
Subject(s) - eosinophilic esophagitis , medicine , propofol , food allergy , allergy , contraindication , egg allergy , retrospective cohort study , incidence (geometry) , logistic regression , dermatology , surgery , pediatrics , immunology , pathology , disease , physics , alternative medicine , optics
Propofol is a safe, well‐tolerated anesthetic that is labeled as contraindicated in patients with egg or soy allergy. This contraindication has become increasingly problematic given the rising incidence of food allergy and eosinophilic esophagitis (EoE). To address this issue, we studied practice patterns of propofol use for esophagogastroduodenoscopies in children with EoE and food allergies at our institution. A retrospective observational study of 1365 esophagogastroduodenoscopies from January 2013 to June 2014 was performed. Data were analyzed using Student t tests, chi square tests, Fisher exact tests, and multivariable logistic regression. We found that propofol was used significantly less in patients with egg or soy allergy, and in patients with EoE, even after adjusting for the presence of food allergy. There was no difference in complication rates relative to propofol use. Propofol was used safely in pediatric patients with EoE and food allergy in this limited single‐center review.