Single-Pattern Convergence of K-ras Mutation Correlates With Surgical Indication of Intraductal Papillary Mucinous Neoplasms
Author(s) -
Osamu Mizuno,
Hirofumi Kawamoto,
Naoki Yamamoto,
Shigeru Horiguchi,
Koichiro Tsutsumi,
Masakuni Fujii,
Hironari Kato,
Ken Hirao,
Naoko Kurihara,
Etsuji Ishida,
Tsuneyoshi Ogawa,
Hiroyuki Okada,
Kazuhide Yamamoto
Publication year - 2010
Publication title -
pancreas
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.061
H-Index - 104
eISSN - 1536-4828
pISSN - 0885-3177
DOI - 10.1097/mpa.0b013e3181c75d9b
Subject(s) - mutation , medicine , gastroenterology , incidence (geometry) , adenoma , carcinoma , pathology , oncology , biology , genetics , gene , optics , physics
One or more patterns of 6 K-ras mutations are detected in cells from the pancreatic juice of patients with intraductal papillary mucinous neoplasms (IPMNs). We investigated whether these mutations are associated with malignant progression.
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