Open AccessInvolvement of Phosphatidylinositol-3 Kinase/AKT/PKCζ/λ Pathway in the Effect of Palmitate on Glucose-Induced Insulin Secretion
Author(s) -
Tatiane C.A. Nogueira,
Gabriel Forato Anhê,
Carla Roberta de Oliveira Carvalho,
Rui Curi,
Silvana Bordin,
Ângelo Rafael Carpinelli
Publication year - 2008
Publication title -
pancreas
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.061
H-Index - 104
eISSN - 1536-4828
pISSN - 0885-3177
DOI - 10.1097/mpa.0b013e318168dac3
Subject(s) - wortmannin , medicine , protein kinase c , protein kinase b , ly294002 , endocrinology , insulin , phosphatidylinositol , pi3k/akt/mtor pathway , phosphorylation , ceramide , chemistry , biology , signal transduction , biochemistry , apoptosis
In the present study, a novel pathway by which palmitate potentiates glucose-induced insulin secretion by pancreatic beta cells was investigated.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom