Open AccessPrimary graft dysfunction
Author(s) -
Mary K. Porteous,
Joshua M. Diamond,
Jason D. Christie
Publication year - 2015
Publication title -
current opinion in organ transplantation
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 0.832
H-Index - 51
eISSN - 1531-7013
pISSN - 1087-2418
DOI - 10.1097/mot.0000000000000232
Subject(s) - medicine , lung transplantation , intensive care medicine , epidemiology , transplantation , extracorporeal , surgery
In 2005, the International Society for Heart and Lung Transplantation published a standardized definition of primary graft dysfunction (PGD), facilitating new knowledge on this form of acute lung injury that occurs within 72 h of lung transplantation. PGD continues to be associated with significant morbidity and mortality. This article will summarize the current literature on the epidemiology of PGD, pathogenesis, risk factors, and preventive and treatment strategies.